Enrico M Novelli, MD, MS, has been appointed as the new Chief of the Division of Classical Hematology in the Department of Medicine, effective May 9, 2024. Dr. Novelli holds the position of Associate Professor of Medicine with Tenure at the University of Pittsburgh School of Medicine. He graduated from the Università Statale di Milano and pursued postdoctoral training in hematology/oncology at Johns Hopkins University, followed by residency training in Internal Medicine and Fellowship in Hematology/Oncology at the University of Pittsburgh.

Dr. Novelli has conducted groundbreaking research on vascular dysfunction in sickle cell disease, with a focus on lesions contributing to vaso-occlusion and the vascular basis of cognitive impairment. His mechanistic interrogations of the pathophysiology of sickle cell disease, using sickle cell mouse models, patients’ biorepositories, and clinical studies, have led to imaging biomarkers that predict and monitor vascular complications through innovative use of cutting-edge MRI and PET technologies. Dr. Novelli has secured continuous NIH funding, including multiple R-series grants, and has served on various committees and panels for the American Society of Hematology and the National Academies of Sciences, Engineering, and Medicine.

Since 2018, Dr. Novelli has led the Section of Benign Hematology. This is one of the largest classical hematology programs in the United States and comprises physician-scientists and research investigators with an international reputation in hemophilia, bleeding disorders, and sickle cell disease. The UPMC Adult Sickle Cell Program is among the largest nationwide, and the hemophilia program benefits from a close partnership with the Hemophilia Center of Western Pennsylvania (HCWP). Additionally, the Section excels in transfusion medicine, iron metabolism, platelet disorders, and rare hematological diseases.

The elevation of the Section of Benign Hematology to the Division of Classical Hematology reflects its national and international reputation and the Department of Medicine’s ongoing commitment to hematology.

Please join us in congratulating the classical hematology faculty on the creation of a new Division and Dr. Novelli on his well-deserved appointment leading the group.