Office:	University of Pittsburgh School of Dental Medicine
	335 Sutherland Drive, Salk Pavilion 508
	Pittsburgh, PA 15261
Phone:	412-648-8535
Fax:
E-mail:	gii5@pitt.edu

Education
	DDS, University of L'Aquila, ITALY, 1995
	Master of Science, University at Buffalo, Buffalo, NY, USA, 2000
	Certificate of Residency in Periodontology, University at Buffalo, Buffalo, NY, USA, 2007
	Doctorate of Philosophy, University at Buffalo, Buffalo, NY, USA, 2007

Training
	Post-doctoral fellowship in Developmental Biology, Harvard School of Dental Medicine, 2012

Research at the laboratory of Dr. Intini (INTINILAB) focuses on skeletal stem cells and on bone cancer stem cells. Genetic strategies and in vivo imaging are utilized to describe the location and function of these cells, and the molecular mechanisms that control their "stemness” in health and disease. • Current skeletal stem cells research: The laboratory has identified the calvarial suture as the niche of osteoprogenitor cells expressing Prx1, a transcription factor highly expressed during embryonic development. Current research, supported by Federal funds (NIH/NIDCR) and by startup funds from the University of Pittsburgh, aims at harnessing these cells to develop novel strategies to foster craniofacial tissue regeneration and to intercept the development of craniofacial malformations (craniosynostosis). Additional projects focus on strategies to utilize Prx1 expressing cells for regeneration of other skeletal regions. • Current bone cancer stem cells research: The laboratory is interested in dissecting the cellular dynamics of osteosarcoma development and metastases. Federal funds (NIH/NCI) have been utilized to generate a novel multifluorescent mouse model of osteosarcoma and startup funds from the University of Pittsburgh are utilized to identify novel strategies to prevent osteosarcoma metastases, the ultimate cause of death in children with this aggressive form of cancer.

As a clinician/periodontist, Dr. Intini has interest in periodontal regeneration and intraoral bone augmentation procedures.

Dr. Intini teaches periodontology and craniofacial biology, and is also involved in mentoring predoctoral and postdoctoral fellows, and clinical research fellows.