Research
The University of Pittsburgh Department of Medicine is a formidable leader in cutting-edge research. Our basic scientists, clinical researchers, and clinicians work daily to make research discoveries that will positively impact the world’s healthcare.
Education and Training
Faculty and staff are actively engaged in training the next generation of physicians and scientists at all stages of medical education.
Clinical
Providing state-of-the-art health care that is compassionate, comprehensive, and easily accessible to patients.
Research from the Cancer Immunotherapeutics Center led by Dr. Jason Luke leads to FDA approval of melanoma treatment
Based on results from the KEYNOTE-716 trial led by Dr. Jason Luke, pembrolizumab resulted in a marked improvement in recurrence-free survival (RFS) and reduced disease recurrence or death by 35%, leading to its approval for treatment of patients 12 years and older...
NIH U54 leads to creation of TriState SenNet Tissue Mapping Center
Led by Drs. Toren Finkel and Melanie Königshoff, the TriState SenNet TMC combines the expertise of faculty from Pitt, CMU, OSU, and URMC to develop a high-resolution map of the senescent cell population in the human lung and heart, define the physiological drivers of senescence, and provide a rational approach to understand the therapeutic potential of senolytic therapy.
Kambez H. Benam develops new robot to simulate vaping effects
To better understand potential damage that emerging vaping products may have on human lungs, Dr. Benam and his team have created a first-in-kind biologically inspired robotic system that quantitatively analyzes submicron and microparticles generated from electronic cigarettes in real-time while mimicking clinically relevant breathing and vaping topography exactly as happens in humans.
NIDDK U01 multidisciplinary grant awarded to DOM faculty for an AKI scientific and data research center
This cross-divisional collaboration among Drs. Kaleab Abebe, Linda Fried, and Paul Palevsky will support the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Consortium, which develops and tests interventions to reduce morbidity among high-risk patients with moderate or severe acute kidney injury.
The Aging Institute’s Bill Chen, PhD, identifies drugs that could combat COVID-19 mutations
In a recent Nature Communications article, the Chen lab discuss how a high-throughput screen could be used to identify FDA-approved compounds that may resist SARS-CoV-2 infection.
Dr. Christopher O’Donnell to head new Office of Emerging Technologies in Health Sciences Education
This new office will advance and enrich interprofessional learning in the health sciences through embracing new technologies from across and beyond the institution while ensuring that technological advances are more integrated, accessible and equitable.