The University of Pittsburgh Department of Medicine is a formidable leader in cutting-edge research. Our basic scientists, clinical researchers, and clinicians work daily to make research discoveries that will positively impact the world’s healthcare.
The grant will allow Dr. Chan and Co-PI Dr. Colleen McClung to study the genetic underpinnings of sleep dysfunction.
Research from the Cancer Immunotherapeutics Center led by Dr. Jason Luke leads to FDA approval of melanoma treatment
Based on results from the KEYNOTE-716 trial led by Dr. Jason Luke, pembrolizumab resulted in a marked improvement in recurrence-free survival (RFS) and reduced disease recurrence or death by 35%, leading to its approval for treatment of patients 12 years and older...
Led by Drs. Toren Finkel and Melanie Königshoff, the TriState SenNet TMC combines the expertise of faculty from Pitt, CMU, OSU, and URMC to develop a high-resolution map of the senescent cell population in the human lung and heart, define the physiological drivers of senescence, and provide a rational approach to understand the therapeutic potential of senolytic therapy.