We are pleased to announce that Daria Van Tyne, PhD has been awarded funding in the amount of $29,873 for a two-year grant by the U.S. Civilian Research & Development Foundation (CRDF Global) entitled “Evolution of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae in the US and Japan Over the Past Two Decades”. This proposal was submitted in response to the 2019 US-Japan Collaborative Award Program for Viral Diseases and Immunology Research. CRDF Global is an independent nonprofit organization that promotes international scientific and technical collaboration, working with more than 40 countries in the Middle East, North Africa, Eurasia, and Asia. CRDF Global specializes in bringing isolated scientific communities into the scientific mainstream through a variety of science engagement and capacity-building programs and encourages science cooperation between countries where official relations are strained.

Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae (EPE) are dominant multidrug-resistant pathogens in both developed and developing countries. EPE are increasing in prevalence, and pose a serious threat to global health because they severely limit the number of antibiotics that can be used to effectively treat them. The goals of this research project are to establish a comprehensive genetic and genomic understanding of EPE in the United States and Japan over the past two decades, and to provide training and mentorship opportunities to the principal investigators and project participants, laying a foundation for future US-Japan collaborative work in the area of antimicrobial resistance. Successful completion of this project will:
1) Generate information that is directly relevant to the treatment and care of patients infected with ESBL-producing pathogens,
2) Establish a framework for future analysis of multidrug-resistantpathogens in other settings, and
3) Form the basis for a new, trans-national collaboration between Dr. Van Tyne and Dr. Miki Nagao of Kyoto University Hospital, who will further their career development through participation in the activities designed for this proposal.

Please join us in congratulating Daria!