Office:	W1055 Biomedical Science Tower
	200 Lothrop Street
	Pittsburgh, PA 15213
E-mail:	endoadm@pitt.edu

Education
	BA, Cornell University College of Arts and Sciences, 1991
	MD, Weill Cornell Medical College of Cornell University, 1997

Training
	Intern, Department of Medicine, New York Presbyterian Hospital- Cornell Campus, 1998
	Resident, Department of Medicine, New York Presbyterian Hospital- Cornell Campus, 2000
	Fellow, Division of Endocrinology, Department of Medicine, Beth Israel Deaconess, 2003
	Instructor, Division of Endocrinology, Department of Medicine, Beth Israel Deaconess, 2008

Dr. Kershaw's academic mission is to forward the understanding and treatment of obesity and related metabolic disorders by combining basic and translational research with clinical expertise. Obesity is a global public health threat that is frequently associated with additional metabolic abnormalities including insulin resistance, glucose intolerance, dyslipidemia, and hypertension (the metabolic syndrome). Together these abnormalities contribute to diseases affecting virtually every organ system. Dr. Kershaw's laboratory focuses on defining the mechanisms by which intracellular lipid metabolism (synthesis, storage, hydrolysis, and oxidation) contributes to obesity and associated metabolic disorders. Most recently, Dr. Kershaw's research efforts have focused on pathways of triacylglycerol hydrolysis (lipolysis) – arguably one of the most fundamental processes in metabolism. Dr. Kershaw is working to define how tissue-specific triacylglycerol hydrolysis contributes to metabolic phenotypes, not only in the metabolic syndrome, but also in variety of other diseases ranging from infertility to cancer. Another major focus of her laboratory is to identify and characterize additional proteins and pathways that contribute to metabolic disease. These efforts fall into two main areas: 1) characterizing novel adipocyte-secreted factors (adipokines) and their relationship to metabolic disease in humans, and 2) characterizing novel genes/loci linked to metabolic disease in humans. Dr. Kershaw's laboratory uses a combination of molecular, cellular, physiological, and translational approaches. The ultimate goal is to develop more effective strategies for prevention and treatment of obesity and associated metabolic disorders.

Dr. Kershaw's clinical interests focus on disorders of "fat," including the following core areas: 1) obesity, insulin resistance, diabetes, and metabolic syndrome, 2) pre- and post-operative care for bariatric surgery patients, 3) lipodystrophies, lipomatoses, and rare adipose tissue disorders, and 4) lipid metabolism and dyslipidemias. Dr. Kershaw is board certified in 1) Endocrinology, Diabetes, and Metabolism by the American Board of Internal Medicine (ABIM), 2) Obesity Medicine by the American Board of Obesity medicine (ABOM), and Clinical Lipidology by the American Board of Clinical Lipidology (ABCL).

Dr. Kershaw's educational mission is to facilitate the career development of trainees in the field of Endocrinology and Metabolism with an emphasis on obesity and its complications. She accomplishes this mission through a combination of didactic coursework, hands-on training, and mentoring. In this way, Dr. Kershaw, has contributed to the scientific and academic development of several trainees ranging from undergraduate students to trainees at the T32 and K level. Several of her prior trainees have subsequently secured independent tenure-track research positions, academic positions, and/or positions in pharmaceutical companies. Dr. Kershaw has held several research training leadership positions including serving as the Associated Program Director for Research for the Clinical Adult Endocrine Fellowship Program, as an oversight committee member for the T32 Training Program in Endocrinology, and as a member of the Physician Scientist Training Program Steering Committee at t he University of Pittsburgh.

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Selected Publications: